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目的观察参芪五味子片健脾益气功效,并初步探讨参芪五味子片对脾虚动物模型免疫系统作用机制。方法将小鼠随机分为空白对照组、脾虚模型组、参芪五味子片扶健组,称量各组脾虚小鼠免疫器官重量并测定外周血T淋巴细胞数量。结果参芪五味子片扶健组免疫器官重量及外周血T淋巴细胞数量均高于脾虚模型组及空白对照组(P<0.05)。结论参芪五味子片增强机体免疫力可能与其增加机体免疫器官重量及增加外周血T淋巴细胞数量有一定关系。
Objective To observe the efficacy of Shenqi Wuweizi Tablets in strengthening spleen Qi and preliminarily explore the mechanism of action of Shenqi Wuweizi Tablet on immune system of spleen deficiency animal model. Methods Mice were randomly divided into blank control group, spleen-deficiency model group, and Shenqi Wuweizi tablet. The weight of immune organs of each group was measured and the number of T lymphocytes in peripheral blood was measured. Results The weight of immune organs and the number of T lymphocytes in peripheral blood of Shenqi Wuweizi Tablets were higher than those in the spleen deficiency model group and blank control group (P<0.05). Conclusion The enhancement of immunity of Shenqi Wuweizi Tablets may be related to the increase of body weight of immune organs and increase of the number of T lymphocytes in peripheral blood.