患儿,男,出生2小时入院,第1胎,胎龄42周,自然分娩,Apgar评分:1及5分钟均为5分。羊水约5000ml,脐带长10cm,呈帆状附着。孕期无病毒感染史。亦无特殊用药史,否认近亲婚配及畸胎遗传史。产前B型超声检查示羊水过多、无脑儿可能性大。X线摄片示颅顶骨缺损,呈不规则骨质致密阴影,脊柱四肢无异常。 Child, male, 2 hours after birth Admission, first child, gestational age 42 weeks, natural childbirth, Apgar score: 5 for 1 and 5 minutes. Amniotic fluid about 5000ml, umbilical cord length 10cm, was sail attached. No history of virus infection during pregnancy. No special drug history, denied the genetic relationship between inbreeding and teratogenic. Prenatal B ultrasound showed too much amniotic fluid, no brain children are more likely. X-ray showed skull defects, irregular dense shadows, spine limbs without exception.