论文部分内容阅读
目的 探讨CAP治疗晚期乳腺癌的疗效和安全性。方法 应用CAP方案治疗晚期乳腺癌 3 8例。初治10例 ,复治 2 8例。结果 全组完全缓解 (CR) 9例 (2 3 .7% ) ,部分缓解 (PR) 16例 (4 2 .1% ) ,总有效率 (CR +PR) 65 .8% ,初治者及复治者有效率分别为 70 .0 %及 64 .3 %。毒副反应主要是恶心 ,呕吐 (71.1% )及白细胞减少 (60 .5 % )。结论 CAP方案治疗晚期乳腺癌有效而安全 ,对复治患者也有较好疗效。
Objective To investigate the efficacy and safety of CAP in the treatment of advanced breast cancer. Methods 38 patients with advanced breast cancer were treated with CAP regimen. 10 cases were initially treated and 28 cases were retreated. Results Complete remission (CR) in 9 patients (23.7%), partial remission (PR) in 16 patients (42.1%), total effective rate (CR +PR) 65.8%, initial management and Relapser effective rates were 70.0% and 64.4%, respectively. The main toxicities were nausea, vomiting (71.1%) and neutropenia (60.5 %). Conclusion The CAP regimen is effective and safe for the treatment of advanced breast cancer, and it also has a good effect on retreatment patients.