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目的:探讨抗中性粒细胞胞浆抗体(ANCA)相关性小血管炎误诊原因。方法:回顾性分析25例ANCA相关性小血管炎患者的临床资料,探讨其临床表现特点及误诊原因。结果:本组ANCA相关性小血管炎误诊平均天数为181d,被误诊为肺炎、肺结核、肺癌、鼻软骨炎、睾丸炎等其他疾病。结论:ANCA相关性小血管炎临床表现缺乏特异性,早期鉴别困难,容易误诊,应重视ANCA检查对诊断的重要意义。
Objective: To investigate the causes of misdiagnosis of anti-neutrophil cytoplasmic antibodies (ANCA) -associated vasculitis. Methods: The clinical data of 25 patients with ANCA-associated vasculitis were analyzed retrospectively to investigate their clinical manifestations and causes of misdiagnosis. Results: The mean number of days misdiagnosed as ANCA-associated vasculitis in this group was 181 days and was misdiagnosed as pneumonia, tuberculosis, lung cancer, nasal chondritis, orchitis and other diseases. Conclusion: The clinical manifestations of ANCA-associated vasculitis are lack of specificity. Early identification is difficult and may be misdiagnosed. The importance of ANCA in the diagnosis should be emphasized.