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目的判断急性心肌梗塞溶栓治疗效果。方法对21例急性心肌梗塞(AMI)患者行溶栓治疗前及治疗后心肌SPECT显像并进行定量分析。将每例患者的左室心肌分为21个节段,在每一节段画一6×6Pixel的ROI,计算每一ROI的放射性计数,以计数最高节段作为100%,其余节段的放射性摄取以最高计数节段的百分值表示。结果患者分为3组,组1为溶栓成功者,共13例,左室心肌共分为273个节段,其中126个节段不正常,按各节段得分总和计算,得分为164±84,溶栓治疗后有45个节段恢复正常(357%),平均得分89±71,较治疗前明显改善(t=252,P<001);组2为溶栓未成功者,共3例,63个节段,其中39个节段不正常,平均得分257±63,与组1间有明显差别(t=177,P<005),经治疗后有2个节段恢复正常(51%),平均得分233±73,与治疗前比较无明显差别(t=043,P>005);组3为未溶栓组,共5例,105个节段,其中52个节段不正常,平均得分176±69,与组1、2间无明显差别(t3、1=038,t3、2=114,P>005),经治疗后有6个节段恢复正常,(?
Objective To determine the effect of thrombolysis in acute myocardial infarction. Methods Twenty-one patients with acute myocardial infarction (AMI) underwent myocardial SPECT before and after thrombolytic therapy and analyzed quantitatively. The left ventricular myocardium of each patient was divided into 21 segments, a 6 × 6 pixel ROI was plotted for each segment, and the radiological counts for each ROI were calculated to count the highest segment as 100% and the remaining segments for radioactivity Ingestion is expressed as a percentage of the highest count segment. Results The patients were divided into 3 groups. Group 1 was successful in thrombolysis, with a total of 13 cases. The left ventricle myocardium was divided into 273 segments, of which 126 segments were abnormal. The score was 16 for each segment. 4 ± 84, 45 segments recovered to normal after thrombolytic therapy (357%), the average score was 89 ± 71, which was significantly improved compared with that before treatment (t = 252, P <0 01). Group 2 was unsuccessful in thrombolysis. There were 3 cases and 63 segments in total, of which 39 segments were abnormal. The average score was 25.7 ± 6.3, which was significantly different from that of group 1 (t = 1 77, P <005). After treatment, 2 segments returned to normal (51%) with an average score of 233 ± 73, no significant difference compared with that before treatment (t = 043 , P> 005); group 3 was not thrombolysis group, a total of 5 cases, 105 segments, of which 52 segments were abnormal, with an average score of 176 ± 69, Obvious difference (t3,1 = 038, t3,2 = 114, P> 0 05), after treatment, six segments returned to normal, (?