返流性食管炎是一种常见病,约占转作内镜检查者的23%,一般症状较轻,但较重者可引起严重的烧心及吞咽困难,可伴有食管狭窄。返流物成份胃酸及胃蛋白酶是引起食管炎的主要因素,但并不是胃及食管返流物的仅有成份。正常人胃内胆汁酸盐浓度为50～500μmol/L,并可高达9mmol/L,在胃切除术的病人,其胃内浓度可升至25mmol/L。有学者证实,食管返流液中可有与胃内相似的胆汁酸盐浓度。返流 Reflux esophagitis is a common disease accounting for about 23% of those turned to endoscopy, with mild symptoms generally, but heavier ones can cause severe heartburn and swallowing difficulties associated with esophageal stenosis. The reflux component stomach acid and pepsin are the main factors that cause esophagitis, but not the only component of the stomach and esophageal reflux. Normal human gastric bile acid concentration of 50 ~ 500μmol / L, and up to 9mmol / L, gastrectomy patients, the stomach concentration can be increased to 25mmol / L. Some scholars have confirmed that esophageal reflux fluid may have similar to the stomach bile acid salt concentration. Backflow