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[目的]评估布克勒(Buchler)137Cs后装腔内放疗机治疗Ⅱ、Ⅲ期宫颈癌的远期疗效。[方法]总结1986年10月至 1987年 12月间应用“Buchler”后装机合并60CO或8MeV直线加速器对Ⅱ、 Ⅲ期的宫颈癌 140例进行根治性放射治疗。放疗剂量:腔内放疗Ⅱ期A点60Gy~72Gy,阴道与宫腔剂量比为4:3或1:1,随后外照射B点则采用盆腔四野照射,剂量44Gy~56Gy。Ⅲ期先采用盆腔全盆大野外照射B点20Gy~29Gy,随后盆腔四野外照射,B点补至456y~55Gy。盆腔四野照射期间配合腔内放疗A点50Gy~60Gy,阴道与宫腔剂量比为3:2或1:1。[结果]全组患者随访10年,其中7人失访,随访率为95%(133/140)。Ⅱ、 Ⅲ期宫颈癌的10年生存率分别为59%(36/61)、31.64%(25/79),总的10年生存率为43.57%(61/140)。[结论]布克勒后装腔内治疗机对宫颈癌的远期疗效比国内报道低,治疗合并症放射性直肠炎、膀胱炎、阴道炎均较高。
[Objective] To evaluate the long-term curative effect of Buchler 137Cs intraocular irradiation machine for treatment of stage II and III cervical cancer. [Methods] From October 1986 to December 1987, 140 patients with stage II and III cervical cancer were treated with “Buchler” combined with 60CO or 8MeV linear accelerator for radical radiotherapy. Radiotherapy dose: endovascular radiotherapy Ⅱ point A point 60Gy ~ 72Gy, vaginal and uterine cavity dose ratio of 4: 3 or 1: 1, followed by external irradiation B point is the use of pelvic four field irradiation dose 44Gy ~ 56Gy. Stage Ⅲ first pelvic basin using the B field point B 20Gy ~ 29Gy, followed by pelvic four field irradiation, B point to 456y ~ 55Gy. Fourteen during pelvic irradiation with intracavitary radiation point A 50Gy ~ 60Gy, vaginal and uterine dose ratio of 3: 2 or 1: 1. [Results] All the patients were followed up for 10 years, of which 7 were lost to follow-up, with a follow-up rate of 95% (133/140). The 10-year survival rates of stage II and stage III cervical cancer were 59% (36/61) and 31.64% (25/79), respectively. The overall 10-year survival rate was 43.57% (61/140). [Conclusion] The long-term curative effect of Buchler posterior endovascular therapy machine on cervical cancer is lower than that reported in China, and radiotherapy proctitis, cystitis and vaginitis are high in the treatment of complications.