早产儿呼吸窘迫综合征是早产儿多发病、病死率高的主要病因。目前多采用外源性肺表面活性物质联合有创性机械通气治疗,效果已得到肯定,但机械通气后,可造成多种相关性并发症[1],例如气压伤[2]、呼吸机相关性肺炎、支气管肺发育不良等。经鼻持续正压通气(NCPAP)保持气道处于一定 Respiratory distress syndrome in preterm infants is the main cause of frequent morbidity and mortality in preterm infants. The current use of exogenous pulmonary surfactant combined with invasive mechanical ventilation has yielded positive results, but after mechanical ventilation, can cause a variety of related complications [1], such as barotrauma [2], ventilator-related Pneumonia, bronchopulmonary dysplasia and so on. Nasal continuous positive pressure ventilation (NCPAP) to maintain airway at a certain