环孢霉素A(Cyclosporin A,CSA)及硝苯吡啶(nifedipine,Ni)最明显的副作用就是导致药物性牙龈增生(dmg induced gingival overgrowth,DGO)。本文的目的是评价牙周手术治疗对于正在服用CSA或Ni并表现出严重的药物性牙龈增生的患者的疗效。 材料和方法 选择38例患者,其中22例属CSA导致的DGO,而由Ni导致的DGO 16例。所有患者均服药6个月以上,而且未服用能导致DGO的其它药物。第一次检查时,对于DGO的情况进行判定并打分。每个患者均接受口腔卫生宣教及洁治, The most obvious side effect of cyclosporin A (CSA) and nifedipine (Ni) is dmg induced gingival hyperplasia (DGO). The purpose of this paper is to evaluate the efficacy of periodontal surgery in patients who are taking CSA or Ni and who exhibit severe, drug-induced gingival hyperplasia. Materials and Methods Thirty-eight patients were selected, of whom 22 were CSA-induced DGO and 16 were DG-induced Ni. All patients took more than 6 months of medication and did not take any other medication that led to DGO. The first inspection, the situation for the DGO to determine and score. Each patient received oral hygiene education and clean governance,