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ADAM家族是近年来发现的一类锚定于细胞膜的细胞表面蛋白家族,该家族成员具有4个较为保守的潜在功能域,在细胞间粘连和融合等活动中有重要作用。迄今为止已有25个成员被发现,它们在精卵结合、肌细胞融合、膜蛋白分子的加工等生理过程中发挥重要功能。
ADAM family is a family of cell surface protein anchored on the cell membrane found in recent years. Members of this family have four more conserved potential domains and play an important role in cell adhesion and fusion. Twenty-five members have so far been found to play an important role in physiological processes such as sperm-egg binding, myocyte fusion, and processing of membrane proteins.