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急性缺血性脑卒中溶栓治疗尚处于初期研究阶段,没有统一的指导性理论,其安全有效性倍受临床医生的关注。现就近年来有关溶栓治疗的研究概况作扼要回顾。 1 溶栓与未溶栓治疗的比较急性缺血性脑卒中早期溶栓治疗,对提高生存率与减少伤残率有积极意义。国外报道早期溶栓治疗显效率47％～81％。北京急救中心应用尿激酶溶栓后24小时及1月后的总有效率为33.3％与60.1％,未溶栓组仅为3.3％与6.7％。溶栓治疗严重并发症为脑出血。Wrardlaw等综述了1573例接受溶栓治疗的患者,出血性发生率为10％,pessin等报道脑梗塞后自然出血率为10％左右,二者无显著差异。
Thrombolytic therapy of acute ischemic stroke is still in the early stage of research, there is no unified guiding theory, and its safety and efficacy are greatly concerned by clinicians. Now on the recent thrombolytic therapy research overview for a brief review. A comparison of thrombolytic and non-thrombolytic treatment of acute ischemic stroke early thrombolytic therapy, to improve survival and reduce the disability rate of positive significance. Foreign reports early thrombolytic therapy markedly effective rate of 47% to 81%. In Beijing First-Aid Center, the total effective rates at 24 and 1 months after thrombolysis with urokinase were 33.3% and 60.1%, respectively, and only 3.3% and 6.7% in those without thrombolysis. Thrombolytic therapy for severe complications of cerebral hemorrhage. Wrardlaw and other reviewed 1573 cases of patients receiving thrombolytic therapy, hemorrhagic incidence was 10%, pessin other reports of natural bleeding after cerebral infarction was 10%, no significant difference between the two.