论文部分内容阅读
非甾体消炎镇痛药萘丁美酮的中间体1-(6-甲氧基-2-萘基)丁-1,3-二酮经一锅法制得。反应催化剂为甲醇钠,易操作制备,重结晶溶剂为乙醇,收率为82%~845%。
The non-steroidal anti-inflammatory analgesic nabumetone intermediate 1- (6-methoxy-2-naphthyl) butane-1,3-dione prepared by one pot. The reaction catalyst is sodium methylate, which is easy to operate and prepared. The recrystallization solvent is ethanol, and the yield is 82% -84.5%.