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目的探讨布洛芬混悬液保留灌肠与口服两种给药方式对于高热儿童退热疗效对比。方法 1岁以上高热儿童,腋温39.1～41.0℃。分为二组,观察组给予布洛芬混悬液保留灌肠;对照组给予布洛芬混悬液口服。二组均按10mg/kg给予布洛芬混悬液,给药后1h、4h复测体温。结果观察组给药后1h、4h复测体温,体温下降至38.5℃以下的百分比为72.5%、90.0%。对照组给药后1h、4h复测体温,体温下降至38.5℃以下的百分比为60.0%、75.0%。二组差异有统计学意义(P<0.05)。结论布洛芬混悬液保留灌肠对高热儿童的退热效果优于布洛芬混悬液口服。
Objective To investigate the efficacy of ileal and oral administration of ibuprofen suspensions for hyperthermia in children. Method 1 year old children with fever, axillary temperature 39.1 ~ 41.0 ℃. Divided into two groups, the observation group was given ibuprofen suspension enema; the control group was given ibuprofen suspension orally. The two groups were given ibuprofen 10mg / kg suspension, administered 1h, 4h after retest body temperature. Results In the observation group, body temperature was measured at 1h and 4h after drug administration, and the percentage of body temperature below 38.5 ℃ was 72.5% and 90.0% respectively. The body temperature of the control group at 1h and 4h after retesting was 60.0% and 75.0% of the body temperature dropped below 38.5 ℃. The difference between the two groups was statistically significant (P <0.05). Conclusion The retention ileum of ibuprofen suspension is better than the ibuprofen suspension in the hyperthermia children.