1病例资料患者,男,36岁,2周前因“咳嗽,咳痰,痰中带血”予我院就诊,患者有外伤史,可见额部皮肤破溃损伤;有吸烟史10年,1~2包/d;饮酒史2~3年,150g/d。胸部X线摄片示:心影饱满,两肺未见明显活动性病变(图1);心电图示窦性心动过速,短P-R间期。1周前出现气促,活动后加重,伴乏力纳差,时有胸闷,逐渐出现双下肢浮肿,夜间不能平卧,伴有阵发性呼吸困难,病程中无发热、盗汗、胸 1 case data, male, 36 years old, 2 weeks ago because of “cough, sputum, bloody sputum ” to our hospital, the patient has a history of trauma, visible amount of skin ulceration injury; a 10-year history of smoking , 1 ~ 2 packages / d; history of drinking 2 to 3 years, 150g / d. Chest X-ray showed: full heart shadow, no significant movement of both lung lesions (Figure 1); ECG shows sinus tachycardia, short P-R interval. 1 week before the onset of shortness of breath, aggravating after activity, with fatigue, poor appetite, chest tightness, gradually lower extremity edema, night can not be supine, accompanied by paroxysmal dyspnea, fever, night sweats, chest