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大鼠经口和大白兔经皮急性毒性试验、大鼠皮肤和大白兔眼刺激试验以及Ａｍｅｓ试验证明：拟原白头翁素９１０５１２－５低毒（ＬＤ（５０）：经口为４６７３．９ｍｇ／ｋｇ。经皮＞２０００ｍｇ／ｋｇ）、对皮肤无刺激性、对眼粘膜有中度刺激作用、系非致突变剂，空内毒，力测定表明。异色瓢虫成虫每头忍受剂量＞９１５０μｇ／ｍｌ，大田常规喷雾有效成分２０ｇ／６６６．７ｍ２剂量下，不影响瓢虫等天敌昆虫种群密度的动态变化。同时根据对鱼低毒的报道，可以初步认为拟原白头翁素９１０５１２－５使用是安全的。
Rat acute oral toxicity and white rabbits toxicity test, rat skin and white rabbits eye irritation test and Ames test proves that: the original original anemones 910512-5 low toxicity (LD (50): oral 4673.9mg / kg Percutaneous> 2000mg / kg), non-irritating to the skin, moderate irritation of the eye mucosa, Department of non-mutagenic agents, empty endotoxic, force determination. The tolerance of insect population per head of Harmonia axyridis> 9150μg / ml, the active ingredient of 20g / 666.7m2 of conventional spray in field did not affect the dynamic change of population density of natural enemies such as lady beetle. At the same time according to reports of low toxicity of fish, you can initially believe that the original original anemones 910512-5 use is safe.