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本文对车间空气中锰年平均浓度为０．１３～０．３３ｍｇ／ｍ３，接锰工龄为１４．８±９．５年的５８名电焊工血清中ＭＤＡ含量及血中抗氧化酶活力进行了研究。结果发现：锰电焊工血清ＭＤＡ浓度为７．８０±２．０５μｍｏｌ／Ｌ对照组为５．５２±３．１８μｍｏｌ／Ｌ，两组间差异有高度显著性（Ｐ＜０．０１）。血中ＧＳＨ－Ｐｘ，ＣＡＴ，红细胞中ＳＯＤ活力与对照组比较差异均无显著性。分工龄组研究发现，ＧＳＨ－Ｐｘ，ＳＯＤ，＞０年工龄组均低于对照组，差异均有显著性（Ｐ＜０．０５）；至＞１０年工龄组回升达对照组水平，两组间差异均无显著性。ＧＳＨ－Ｐｘ，ＳＯＤ活力与接锰工龄呈正相关，ｒ分别为０．４９９，０．３６４，有显著意义和非常显著意义（Ｐ＜０．０１，０．０５）。
In this paper, the average annual concentration of manganese in the air of the workshop was 0.13 ~ 0.33mg / m3, then the MDA content of 58 welders’ sera and the activity of antioxidant enzymes in the blood of 14.8 ± 9.5 years were compared the study. The results showed that serum MDA concentration of manganese welders was 7.80 ± 2.05μmol / L and 5.52 ± 3.18μmol / L in control group, with a significant difference between the two groups (P <0.01). GSH-Px, CAT in blood, SOD activity in erythrocytes were not significantly different from the control group. According to the study of different age groups, GSH-Px, SOD,> 0 years of age group were lower than the control group, the difference was significant (P <0.05); up to> 10 years of age group returned to the control group level, There was no significant difference between the two groups. The activities of GSH-Px and SOD were positively correlated with the length of Mn-graft service, with r values of 0.499 and 0.364, respectively, which were significant and significant (P <0.01, 0.05).