目的:了解高原地区精神病专科医院收治精神病患者合并丙肝抗体阳性情况,对丙型肝炎感染提出防范措施。方法:对我院收治的合并丙肝抗体阳性的精神病患者的临床资料进行分析。结果:期间我院共收治精神病患者5 535例,合并丙肝抗体阳性的患者38例,检出率0.69%。结论:精神病合并丙肝抗体阳性率较高,普及丙肝防治知识、做好入院筛查、积极预防和有效管理,减少丙型肝炎传播。 Objective: To understand the prevalence of hepatitis C antibody positive patients with mental illness in psychiatric hospitals in plateau area and to provide preventive measures for hepatitis C infection. Methods: The clinical data of patients with psychosis who had hepatitis C antibody positive in our hospital were analyzed. Results: During the period, 5 535 psychiatric patients were admitted to our hospital, and 38 patients were positive with hepatitis C antibody. The detection rate was 0.69%. Conclusion: The positive rate of hepatitis C antibody in patients with psychosis is high, popularizing the knowledge of prevention and treatment of hepatitis C, screening well, preventing and managing effectively and reducing the spread of hepatitis C.