急性胰腺炎(AP)的特征是可能从局部炎症发展至全身性炎症反应综合征,最后可导致多器官功能衰竭。尽管目前提出了多种AP病理生理机制,但未完全明确。对NF-κB、ROS及细胞信号途径等信号调节的分子机制的研究,将为AP的治疗提供新的靶向和策略。 Acute pancreatitis (AP) is characterized by the potential to develop from local inflammation to systemic inflammatory response syndrome, which can eventually lead to multiple organ failure. Although a variety of AP pathophysiological mechanisms are currently proposed, they are not entirely clear. The study of the molecular mechanisms of signal regulation such as NF-κB, ROS and cell signaling pathways will provide new targets and strategies for the treatment of AP.