Furegrelate是一种血栓素合成酶抑制剂。作者研究了本品在人体内的作用。24名健康男性志愿者参加随机、单盲、安慰剂对照试验,服用剂量为200、400、800或1600mg,每12小时1次,共4.5天。定期抽取血样,加入花生四烯酸100～400μg/ml后3.5～4分钟测定富血小板血浆中血栓素合成酶活性和血小板聚集作用基值,培养1小时后再测定血栓素合成酶活性。结果表明,本品对 Furegrelate is a thromboxane synthase inhibitor. The author studied the role of this product in the human body. Twenty-four healthy male volunteers participated in a randomized, single-blind, placebo-controlled trial of 200, 400, 800 or 1600 mg every 12 hours for a total of 4.5 days. Blood samples were taken periodically, and the thromboxane synthase activity and platelet aggregation value in platelet-rich plasma were measured 3.5 to 4 minutes after the addition of arachidonic acid at 100-400 μg / ml. Thromboxane synthetase activity was measured after 1 hour of culture. The results show that this product right