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根据体外反搏可能增加肝、肾血流量的原理,并根据临床上每次体外反搏治疗后病人尿量明显增多的事实,本室于1987年年底起,开始对体外反搏治疗病毒性肝炎的疗效及其机理进行了研究,先后共治疗各型病毒性肝炎33例,包括急性肝炎15例(其中重症肝炎恢复期4例、顽固型甲肝5例、顽固型乙型6例),慢性肝炎17例(其中迁肝9例、慢活肝8例),妊娠胆汁瘀积型肝炎1例。治疗目的是针对大多数病人持续高胆红素血症和高谷丙转氨酶血症;对部分病人则针对严重的失眠与全身不适,碱性磷酸酶活性升高。本治疗效果十分满意,总有效率达63％,有望成为难治性肝炎病例的一种有效的新辅助疗法。
According to the principle that extracorporeal counterpulsation may increase the blood flow of liver and kidney, and according to the fact that the urine volume of the patient increases significantly after each extracorporeal counterpulsation in clinic, the chamber began to treat viral hepatitis Of the efficacy and mechanism were studied in 33 cases of various types of viral hepatitis, including 15 cases of acute hepatitis (including 4 cases of severe hepatitis convalescence, 5 cases of stubborn type of hepatitis B, 6 cases of refractory type B), chronic hepatitis 17 cases (including 9 cases of moving liver, 8 cases of slow living liver), 1 case of cholestatic hepatitis. The aim of treatment is to continue hyperbilirubinemia and alanine aminotransferasemia in most patients; to some patients, for severe insomnia and general malaise, alkaline phosphatase activity is increased. The treatment is very satisfactory, with a total effective rate of 63%, is expected to become a case of refractory hepatitis, an effective neoadjuvant therapy.