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目的 :探索肠内营养乳剂(瑞先)对慢性阻塞性肺疾病(COPD)患者营养指标的影响。方法 :在重症监护室住院的60例COPD患者,按照随机数字法分为试验组和对照组,试验组以口服瑞先为肠内营养,对照组口服自制流质。观察的营养指标包括白蛋白、前白蛋白、转铁蛋白。结果 :治疗10d后,试验组上述指标较治疗前有明显改善。对照组较治疗前营养指标亦有所改善,但试验组的营养改善幅度高于对照组。试验组与对照组比较,腹泻、饱胀、恶心、呕吐等不良反应发生率差异,无统计学意义(P>0.05)。结论 :肠内营养乳剂(瑞先)能显著改善老年科住院的COPD患者的营养状况,且耐受性良好。
Objective: To explore the effect of enteral nutrition emulsion (Ruixian) on nutritional parameters in patients with chronic obstructive pulmonary disease (COPD). Methods: Sixty COPD patients hospitalized in intensive care unit were divided into experimental group and control group according to random number method. The experimental group took enteral nutrition by oral administration and oral liquid by oral administration. Nutritional indicators observed include albumin, prealbumin, transferrin. Results: After 10 days of treatment, the above indexes in the experimental group were significantly improved compared with those before treatment. The control group also improved the nutritional index before treatment, but the nutrition improvement rate of the experimental group was higher than that of the control group. There was no significant difference in the incidence of adverse reactions such as diarrhea, fullness, nausea and vomiting between the experimental group and the control group (P> 0.05). Conclusion: Enteral nutrition emulsion (Ruixian) can significantly improve the nutritional status of COPD patients in the geriatric department and are well tolerated.