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应用非特异性刺激药物乙酰甲胆碱喷雾于鼻粘膜,测定鼻粘膜过敏的程度,试用于非过敏性鼻炎伴嗜酸性粒细胞增多综合征(NARES)的诊断。主诉有长年鼻变态反应症状(鼻塞、水性鼻涕、喷嚏)患者101例为对象,男46例,女55例,年龄11～72岁,平均38.4岁。变态反应性诊断,是用14种吸入变应原皮肤作划痕试验,再用6种变应原作吸入抗原,然后测定鼻涕中嗜酸性粒细胞数,及血清IgE RIST值,IgE RAST记分;再行鼻粘膜抗原诱发试验及乙酰甲胆碱作鼻诱发试验,按上述检查结果,将慢性鼻炎患者分为3组。
The nonspecific stimulation drug methacholine is sprayed on the nasal mucosa to determine the degree of nasal mucosal allergy and is used in the diagnosis of non-allergic rhinitis with eosinophilia syndrome (NARES). The main complaint was long-term nasal allergy symptoms (nasal obstruction, watery nose, sneezing) in 101 patients, 46 males and 55 females, aged from 11 to 72 years, mean 38.4 years. Allergen diagnosis is the use of 14 kinds of inhaled allergen skin scratch test, and then six kinds of allergens for inhaled antigen, and then determine the number of nasal discharge eosinophils, and serum IgE RIST value, IgE RAST score; and then Nasal mucosal antigen induction test and methacholine nasal induction test, according to the above test results, the chronic rhinitis patients were divided into 3 groups.