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目的单采血小板与混合浓缩血小板的质量指标与临床疗效比较。方法采用富血小板血浆法制备混合浓缩血小板,分析血小板输注患者的一般资料,对其进行血小板数值检测。借助血小板纠正计数指数(CCI)开展临床疗效评估工作。结果混合浓缩血小板的平均计数为(3.3±0.9)×1011,合格率100%,单采血小板的平均计数为(2.6±0.1)×1011,合格率为98.2%;单采血小板组有效率CCI为90.4%,;混合浓缩血小板组有效率CCI为89.8%。2组输注后1 h CCI、24 h CCI临床出血症状疗效比较,差异无统计学意义(P>0.05)。结论单采血小板与混合浓缩血小板质量无统计学意义,均能够提升外周血中的血小板数量,实现治疗作用,规避大出血并发症。
Objective To compare the quality indexes and clinical curative effect between single apheresis platelets and mixed platelet concentrates. Methods Mixed platelets were prepared by platelet-rich plasma method, and the general data of platelet transfusion patients were analyzed. The platelet count was measured. With the platelet correction count index (CCI) to carry out clinical efficacy evaluation. Results The average concentration of mixed platelets was (3.3 ± 0.9) × 1011, the pass rate was 100%. The average number of apheresis platelets was (2.6 ± 0.1) × 1011, the pass rate was 98.2% 90.4%. The effective rate of CCI was 89.8% in mixed PLT group. There was no significant difference in the clinical efficacy of CCI and CCI after 1 hour of infusion between 2 groups (P> 0.05). Conclusion There is no significant difference between single platelet and mixed platelet concentrates, which can increase the number of platelets in peripheral blood and achieve the therapeutic effect and avoid the complications of hemorrhage.