本文报告我院建立了人胎胰组织培养方法,并应用短期培养的人胚胎胰岛组织为20例Ⅰ型糖尿病患者施行了胰岛移植。移植部位均为小网膜腔内。移植最长时间26个月,最短时间4个月,总有效率90%。平均胰岛素每日用量比移植前明显减少50%以上,同时空腹血糖等参数明显下降,血清 C 肽值增长2～4倍。移植前后均未服免疫抑制剂,移植物保持良好的功能,未发生排斥现象。 This article reports our hospital established a method of human fetal pancreatic tissue culture, and the application of short-term cultured human embryonic islet tissue for the implementation of 20 cases of type I diabetes in patients with islet transplantation. Transplanted sites are small omentum. Transplantation of the longest time of 26 months, the shortest time of 4 months, the total efficiency of 90%. The average daily dosage of insulin significantly reduced more than 50% before transplantation, while fasting blood glucose and other parameters decreased significantly, serum C-peptide increased 2 to 4 times. Immunosuppressive agents were not administered before and after transplantation, and the graft maintained good function without rejection.