自从1969年Cotzias报导左旋多巴治疗震颤麻痹获得显效以来,此药已迅速成为治疗本病的主要药物。然而,长期随访用左旋多巴治疗的患者的结果表明,此种治疗远不符合理想。 Since 1969 Cotzias reported effective treatment of paralytic levodopa has been effective, the drug has rapidly become the main drug for the treatment of this disease. However, the results of long-term follow-up of patients treated with levodopa suggest that this treatment is far from satisfactory.