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目的:对采用甲氨喋呤联合米非司酮治疗异位妊娠45例临床患者进行观察研究。方法:随机选择本院2015年10月-2016年10月接受异位妊娠治疗的90例患者进行研究,随机分为观察组和治疗组各45例,观察组患者口服米非司酮进行治疗,治疗组患者在口服米非司酮的基础上加用甲氨喋呤,比较两组患者的的治疗效果以及治疗中各项指标的变化。结果:采用甲氨喋呤联合米非司酮治疗的治疗组患者的总有效率约为84%,单用米非司酮治疗的患者总有效率约为55%,治疗组患者的血HCG的下降程度和盆腔包块缩小程度明显大于观察组(P<0.05)。结论:使用甲氨喋呤联合米非司酮对异位妊娠进行治疗,其效果明显优于单用米非司酮,更值得推广与应用。
Objective: To observe and study 45 cases of ectopic pregnancy treated with methotrexate and mifepristone. Methods: Ninety patients randomly selected from our hospital for treatment of ectopic pregnancy from October 2015 to October 2016 were randomly divided into observation group (n = 45) and treatment group (n = 45). Patients in observation group were treated with mifepristone, The patients in the treatment group were given methotrexate on the basis of oral mifepristone, and the treatment effect and the changes of various indexes in the two groups were compared. Results: The total effective rate of patients treated with methotrexate combined with mifepristone was about 84%. The total effective rate of patients treated with mifepristone was 55%. The blood HCG The extent of decrease and pelvic mass shrinkage were significantly greater than the observation group (P <0.05). Conclusion: Methotrexate combined with mifepristone for the treatment of ectopic pregnancy, the effect was significantly better than mifepristone alone, more worthy of promotion and application.