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分别用光镜、电镜观察41例和5例腺泡细胞癌(Acc)。结果显示:ACC中含多种不同分化的细胞成分,腺泡样细胞和闰管样细胞分化成熟,类似于正常腺体的超微结构;“透明细胞”实际为上述两种细胞的变性,非特异性“多潜能”储备细胞,缺乏细胞器,核浆比例失调属未分化的细胞,这种细胞对肿瘤分化有重要意义,且ACC来源于这种细胞的不同方向分化。88.7%的ACC中存在微囊,细胞内微囊来自细胞器变性;粗面内质网扩张;次级溶酶体变性融合,光镜下的细胞间微囊实际来自变性细胞的破裂;含空泡的细胞突位于细胞间及含微绒毛突起的真性管腔。
Light and electron microscopy were used to observe 41 cases and 5 cases of acinar cell carcinoma (Acc). The results showed that: ACC contains a variety of differently differentiated cellular components, acinar-like cells and fistula-like cells differentiate and mature, similar to the ultrastructure of the normal gland; “transparent cells” are actually the degeneration of these two types of cells, non-special Heterologous “pluripotent” reserve cells, lack of organelles, unregulated plasma and plasma ratios, are important for tumor differentiation, and ACC is derived from the differentiation of these cells in different directions. The microcapsules were present in 88.7% of ACCs. The intracellular microcapsules were degenerated by organelles; the rough endoplasmic reticulum was expanded; the secondary lysosomal degeneration was fused, and the intracellular microcapsules under light microscopy actually originated from the rupture of degenerating cells; Voided cell processes are located between the cells and the true lumen containing microvillus.