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St14-1(DXS52)是位于人X染色体长臂远端的一段DNA顺序,与第Ⅷ凝血因子(FⅧ:C)基因紧密连锁.用其作探针,BcII酶切,对人基因组DNA进行Southern印迹杂交分析,可检测到一限制性片段长度多态性(RFLP).我们分析广东地区汉族人群中st14/BcII RFLP,等位基因片段长度分别为17.4kb和16·6kb(见附图).15条无遗传关系的X染
St14-1 (DXS52) is a DNA sequence located at the far end of the long arm of human X chromosome and closely linked to the gene VIII (FⅧ: C) gene.It is used as a probe for BcII digestion and Southern blotting of human genomic DNA A restriction fragment length polymorphism (RFLP) was detected by Western blot analysis.We analyzed the st14 / BcII RFLP in Guangdong Han population, the length of the allele was 17.4kb and 16.6kb, respectively (see the attached figure). 15 non-genetic relationship X dye