1875年Laqueur首次应用毒扁豆硷治疗青光眼,能使眼压降低。此后其他药物相继应用,都有不同程度的降压作用,但多数属于縮瞳剂。近十余年来降低眼压的药物有了很大进展,不仅品种增加,其作用机制也逐漸闡明。有关这方面的知識一向是药工同志們所关心的,本文特作一綜述介紹。 1875 Laqueur first treatment of glaucoma with physostigmine, can make Iow pressure reduction. Since then, other drugs have been applied, have different degrees of antihypertensive effect, but most are miotic agents. Nearly more than a decade to reduce intraocular pressure has made great progress in drugs, not only increased variety, its mechanism of action has gradually elucidated. Knowledge in this area has always been the concern of the medical and pharmaceutical comrades, this article specially for a brief introduction.