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目的在2型糖尿病患者与非2型糖尿病人群中,明确代谢综合征(Met S)与踝臂指数(ABI)的相关性。方法 356例患者,其中代谢综合征184例,无代谢综合征172例。计算各代谢综合征包含因素个数和各代谢综合征及糖尿病(DM)分组的ABI值。多元线性回归模型分析非糖尿病及糖尿病人群中,代谢综合征与ABI的相关性。结果随着代谢综合征包含因素个数的增加,ABI值呈现出下降的趋势(P=0.009);代谢综合征及糖尿病均为(-)的人群ABI最高,代谢综合征及糖尿病均为(+)的人群ABI最低,各分组的ABI值比较差异具有统计学意义(P=0.019)。在非糖尿病人群中,在经过年龄、性别、低密度脂蛋白及吸烟的校正后,代谢综合征并不与ABI显著相关(P=0.328)。在糖尿病人群中,在校正上述影响因素后,代谢综合征与ABI显著相关(P=0.011)。结论在糖尿病患者中,代谢综合征与ABI存在相关性,但在非2型糖尿病患者中,这种相关性并未存在。
Objective To determine the relationship between Met S and ABI in type 2 diabetic and non-type 2 diabetic patients. Methods 356 patients, including metabolic syndrome in 184 cases, 172 cases without metabolic syndrome. Calculate the number of factors involved in each metabolic syndrome and the ABI values for each of the metabolic syndrome and diabetes mellitus (DM) groups. Multivariate linear regression model was used to analyze the association of metabolic syndrome with ABI in non-diabetic and diabetic populations. Results With the increase of the number of factors of metabolic syndrome, the ABI value showed a decreasing trend (P = 0.009); ABI was highest in metabolic syndrome and diabetes mellitus (-), metabolic syndrome and diabetes mellitus were (+ ) Had the lowest ABI, and the differences of ABI in each group were statistically significant (P = 0.019). Metabolic syndrome was not significantly associated with ABI in non-diabetic subjects after correction for age, sex, LDL, and smoking (P = 0.328). In the diabetic population, metabolic syndrome was significantly associated with ABI (P = 0.011) after adjusting for the above effects. Conclusion There is a correlation between metabolic syndrome and ABI in patients with diabetes, but this correlation does not exist in non-type 2 diabetic patients.