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为探讨载体与人骨形态发生蛋白（ｈＢＭＰ）活性的关系并为今后临床提供有价值的资料，本实验用小样本观察了ｂＤＤＢＭ．ｒＤＤＢＭ、ｈＤＤＢＭ、Ｃｏｌｌａ．Ｉ、ＨＡＰ．Ｃａ３（ＰＯ４）２六种载体、大样本观察了六种载体中的三种（ｈＤＤＢＭ、ｒＤＤＢＭ、Ｃ（ＰＯ４）和第七种ＢＭＰ载体与ｈＢＭＰ诱导成骨的关系。发现，无ＢＭＰ活性、脱矿物质的人脱矿骨基质（ｈＤＤＢＭ）与ｈＢＭＰ的复合物具有最佳活性。ｈＤＤＢＭ在扫描电镜下具有多孔结构，其平均孔径为１２７±３４ｍ。结果显示，无ＢＭＰ活性、脱矿物质的骨基质（ＤＤＢＭ）的性能不仅与ＤＤＢＭ的孔径大小有关，而且与基质中纤维样物质的含量有关。此外，还发现在对ＢＭＰ进行活性检验时，如采用将ＢＭＰ和载体的复合物注入小鼠小腿三头肌内的方法，可使对ＢＭＰ的活性检验更为简单、可靠。
In order to explore the relationship between vector and human bone morphogenetic protein (hBMP) activity and to provide valuable data for future clinical trials, bDDBM was observed with a small sample in this experiment. rDDBM, hDDBM, Colla. I, HAP. Ca3 (PO4) 2, a large sample of three of the six vectors was observed (hDDBM, rDDBM, C (PO4), and the seventh BMP vector in relation to hBMP-induced osteogenesis. The mineralized human demineralized bone matrix (hDDBM) has the best activity with the hBMP complex.HDDBM has a porous structure under a scanning electron microscope with an average pore size of 127 ± 34 m.The results show that BMP-free, demineralized bone The performance of the matrix (DDBM) is not only related to the pore size of DDBM, but also to the content of fiber-like substances in the matrix.Moreover, it has also been found that in the activity test of BMPs, such as the injection of a complex of BMP and carrier into the mouse leg Triceps intramuscular method can make the test of BMP activity more simple and reliable.