依达拉奉用于治疗急性脑梗死的疗效分析

来源 :中国临床研究 | 被引量 : 0次 | 上传用户:vbsunboy
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目的观察自由基清除剂依达拉奉治疗急性脑梗死的疗效。方法选择2009年3月至2011年2月100例急性脑梗死患者,随机分为治疗组(50例)和对照组(50例),治疗组予常规治疗基础上加用依达拉奉;对照组予常规治疗基础上加舒血宁注射液治疗。两组均在治疗前和治疗第7日及21日进行神经功能缺损评分及疗效评定。结果治疗组治疗第7日总有效率为90.0%,第21日为98.0%;对照组治疗第7日总有效率为66.0%,第21日为72.0%;各时间点两组比较差异有统计学意义(P均<0.05)。治疗组1例用药中出现左心功能不全表现。结论依达拉奉治疗急性期脑梗死可取得良好疗效。 Objective To observe the efficacy of free radical scavenger edaravone in the treatment of acute cerebral infarction. Methods 100 patients with acute cerebral infarction from March 2009 to February 2011 were randomly divided into treatment group (50 cases) and control group (50 cases). The treatment group was treated with edaravone on the basis of conventional treatment. The control group On the basis of conventional treatment, Shu Shuxuening injection was given. Both groups were evaluated before treatment and on the 7th and 21st on the neurological deficit score and the curative effect. Results In the treatment group, the total effective rate was 90.0% on the 7th day and 98.0% on the 21st day. In the control group, the total effective rate was 66.0% on the 7th day and 72.0% on the 21st day. There was statistical difference between the two groups at each time point Significance (P <0.05). One case of treatment group showed left ventricular dysfunction in medication. Conclusion Edaravone can treat acute cerebral infarction with good curative effect.
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