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目的:分析LEPP刀用于宫颈上皮内瘤变(CIN)治疗中的临床效果。方法:选取我院收治的CIN患者共40例,依照入院顺序随机、评价分为治疗组与对照组,治疗组予以LEEP刀治疗,对照组予以传统激光治疗,对照两组患者临床疗效。结果:对照组患者治愈12例、有效5例、无效3例,治愈率60.0%、总有效率85.0%;治疗组患者治愈18例、有效2例、无效0例,治愈率90.0%、总有效率100.0%,治疗组治愈率及总有效率均高于对照组(P<0.05)。对照组平均治疗时间、术中出血量、术后焦蹦脱落出血量、愈合时间分别为(12.3±1.3)min、(5.8±1.1)ml、(5.7±1.2)ml、(9.7±1.6)d,治疗组平均治疗时间、术中出血量、术后焦蹦脱落出血量、愈合时间分别为(6.2±1.1)min、(1.4±0.7)ml、(2.5±0.7)ml、(5.2±0.4)d,治疗组治疗时间及愈合时间均短于对照组、术中出血量和术后焦蹦脱落出血量均少于对照组(P<0.05)。结论:LEEP刀治疗CIN可缩短治疗时间、愈合时间,还可减少术中出血、术后焦蹦脱落出血量,治愈率及有效率更高,值得在妇科临床推广应用。
Objective: To analyze the clinical effect of LEPP knife in the treatment of cervical intraepithelial neoplasia (CIN). Methods: Forty patients with CIN admitted to our hospital were randomly divided into treatment group and control group. The patients in the treatment group were treated with LEEP knife and the control group with conventional laser treatment. The clinical efficacy of the two groups were compared. Results: In the control group, 12 cases were cured, 5 cases were effective and 3 cases were ineffective. The cure rate was 60.0% and the total effective rate was 85.0%. In the treatment group, 18 cases were cured, 2 cases were effective, 0 was ineffective and the cure rate was 90.0% The efficiency was 100.0%. The cure rate and total effective rate in the treatment group were higher than those in the control group (P <0.05). The average duration of treatment, intraoperative blood loss, postoperative coke jumped off bleeding and healing time were (12.3 ± 1.3) min, (5.8 ± 1.1) ml, (5.7 ± 1.2) ml, (9.7 ± 1.6) d (6.2 ± 1.1) min, (1.4 ± 0.7) ml, (2.5 ± 0.7) ml, (5.2 ± 0.4) ml, and (5.2 ± 0.4) ml respectively.The mean time of treatment, d, the treatment group treatment time and healing time were shorter than the control group, the amount of intraoperative blood loss and postoperative jiao jump off bleeding were less than the control group (P <0.05). Conclusion: LEEP knife treatment of CIN can shorten the treatment time, healing time, but also reduce intraoperative bleeding, jiao jumped off bleeding after surgery, the cure rate and higher efficiency, it is worth in the gynecological clinical application.