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血管扩张剂对充血性心力衰竭有益的血流动力学效应,提示其血管张力的异常增加可能是本病自然病史中的一个重要因素。这种血管阻力升高很可能有交感神经系统和肾素-血管紧张素系统的参与。本文报道口服单次剂量溴麦角环肽(已知能抑制去甲肾上腺素的释放)在10例慢性充血性心力衰竭患者中的效用。方法:10例患者均为男性,年龄34～75岁。7例为缺血性心脏病,3例为特发性充血性心肌病。心功能Ⅱ～Ⅳ级,X 线和超声心动图示左室扩大,心
The beneficial hemodynamic effects of vasodilators on congestive heart failure suggest that an abnormal increase in vascular tone may be an important factor in the natural history of the disease. This increased vascular resistance is likely to involve the sympathetic nervous system and the renin-angiotensin system. This article reports the utility of oral single doses of bromocriptine, known to suppress the release of norepinephrine, in 10 patients with chronic congestive heart failure. Methods: All 10 patients were male, aged 34 to 75 years. 7 cases of ischemic heart disease, 3 cases of idiopathic congestive cardiomyopathy. Cardiac function Ⅱ ~ Ⅳ level, X-ray and echocardiography showed left ventricular enlargement, heart