高血压的药物治疗已有30多年历史,从五十年代的神经节阻断药肼苯哒嗪、利血平和利尿剂,发展到六十年代的中枢降压药、β阻滞剂和α阻滞剂,七十年代又发现了钙拮抗剂和转化酶抑制剂。从药理性质或作用机制来看,这些药物的作用可分为四类:(1)作用于交感神经系统;(2)作用于血管平滑肌;(3)影响肾功能;(4)抑制肾素-血管紧张素系统。今天,抗高血压药物已有上百个,而且新药还在不 Antihypertensive drugs have been in place for more than 30 years and have been shown to block the development of central antihypertensives, beta blockers, and alpha blockers from the ganglia of the fifties blocking the drugs hydralazine, reserpine and diuretics Defibrillators, the seventies and found calcium antagonists and invertase inhibitors. Pharmacological properties or mechanism of action, the role of these drugs can be divided into four categories: (1) the role of the sympathetic nervous system; (2) on vascular smooth muscle; (3) affect renal function; (4) inhibition of renin - Angiotensin system. Today, there are hundreds of antihypertensive drugs, and new drugs are still not