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采用简易免疫电镜方法，从我国新疆非甲非乙型（戊型，ＨＥ）肝炎病人粪悬液中检出含有小圆形病毒颗粒的阳性标本５例，经细胞培养，从接种含病毒的２ＢＳ细胞中分离到一株能引起细胞病变、具有血凝活性的病毒（８７Ａ株）。电镜下可见感染细胞胞浆中呈现局灶性空泡、液泡病变区，并含晶格样排列的圆形病毒颗粒，核变形。该株病毒能被新疆疫区以及来自缅甸、印度、前苏联ＨＥ病人血清及美国接种ＨＥ病毒的黑猩猩急性期血浆所聚集，显示其间有密切血清学关系，提示该株病毒为我国新疆ＨＥ的致病病原。该病毒大小约３０ｎｍ，圆形，表面形态结构特殊；装配成熟过程与粗面内质网、包涵体、微丝等密切相关；病毒因细胞破碎而释放。这些形态及形态发生特征与嵌杯病毒科病毒相近。我们认为应归嵌杯病毒科新属成员。
A simple immunoelectron microscopy method was used to detect positive samples containing small round virions from the fecal suspensions of non-A, non-A (HEV) hepatitis patients from Xinjiang in China. Five cell lines were infected with 2BS A virus that causes cytopathic and haemagglutinating activity was isolated from cells (87A strain). Electron microscopy showed that the cytoplasm of infected cells showed focal vacuoles and vacuolar lesions, and contained round-shaped virus particles that arranged in a lattice-like pattern with nuclear deformation. This strain of virus can be collected from the epidemic areas of Xinjiang and from the plasma of HE patients from Burma, India, the former Soviet Union and chimpanzees inoculated with HE virus in the United States, indicating that there is a close serological relationship between the strains of virus and the HE in Xinjiang of our country Pathogen. The size of the virus is about 30nm, round, special surface morphology; assembly maturation process and rough endoplasmic reticulum, inclusions, microfilaments are closely related; virus release due to cell disruption. These morphological and morphogenetic features are similar to those of the Family Valvirus. We think we should belong to the new genera of members of the family.