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目的：采用ＡＢ／ＰＡＳ，ＨＩＤ／ＡＢ／ＰＡＳ，以及多种抗人结肠粘液癌相关抗原的单克隆抗体（ＭＣＡｂｓ）对９２例大肠粘液癌进行组织化学和免疫组织化学的比较研究。方法：以阿尔新蓝过碘酸雪夫（ＡＢ／ＰＡＳ）和高铁二胺阿尔新蓝过碘酸雪夫（ＨＩＤ／ＡＢ／ＰＡＳ）组化法及单克隆抗体（ＭＣＡｂｓ）、癌胚抗原（ＣＥＡ）、抗大肠癌单克隆抗体ＳＣ３Ａ、ＳＣ６和ＳＣ１３Ａ与６２例粘液癌和３０例印戒细胞癌进行染色标记。结果：两种方法所显示的各种染色的成份大致相同。在４种ＭＣＡｂｓ与两组癌细胞的反应中ＳＣ６和ＳＣ１３Ａ与粘液癌结合的阳性率均高于ＣＥＡ和ＳＣ３Ａ，且ＳＣ６在粘液癌中明显高于ＣＥＡ。结论：ＭＣＡｂｓ、ＳＣ６及ＳＣ１３Ａ对大肠粘液癌的诊断价值比ＣＥＡ反应高，是优于ＣＥＡ的肿瘤标记物。
Objective: AB PAS HID / AB / PAS, and comparative study /, mucinous more anti-human colon cancer-associated antigen monoclonal antibodies (McAbs) 92 cases of colorectal cancer, mucinous histochemical and immunohistochemical employed. Methods: Alcian blue periodic acid Schiff (AB / PAS) and a high iron diamine Alcian blue periodic acid Schiff (HID / AB / PAS) staining and monoclonal antibodies (McAbs), carcinoembryonic antigen (CEA) The colorectal cancer monoclonal antibodies SC3A, SC6, and SC13A were stained with 62 mucinous carcinomas and 30 signet-ring cell carcinomas. Results: The various dyeings shown by the two methods have roughly the same composition. In the reaction with two 4 kinds MCAbs cancer and positive rates SC6 SC13A mucinous cancers than in combination with CEA and SC3A, mucinous carcinoma and SC6 in significantly higher than CEA. Conclusion: The diagnostic value of MCAbs, SC6 and SC13A for mucinous carcinoma of the large intestine is higher than that of CEA. It is a tumor marker superior to CEA.