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缝隙连接是构成多细胞器官的细胞间普遍存在的亲水性通道,它介导的细胞间通讯的降低和丧失对细胞增殖有一定的作用,导致肿瘤的发生。连接蛋白是构成缝隙连接通道的基本结构和功能蛋白,其表达数量和类型在脑组织发育过程中有一定差异。
The gap junction is a common hydrophilic channel among the cells that make up multicellular organs. It mediates the decrease and loss of cell-to-cell communication and plays a role in cell proliferation, leading to the tumor. Connexin is the basic structure and functional protein that make up the gap junctional channel. The quantity and type of connexin are different in the development of brain tissue.