脊索瘤是一罕见肿瘤,起源于残余的胚胎脊索,沿脑脊髓轴生长。本病约50%发生于骶尾部,35%发生于蝶骨底区,15%发生于椎体。其大体标本为分叶的囊状肿块内有纤维膈和胶状物。镜下瘤细胞呈散乱状排列,通常不规则及空泡状,也可呈粘液或淀粉样变。有些细胞分化较差但大多没有核分裂。材料与方法:自1948年至1976年安德森医院收治了19例脊索瘤,年龄在4-80岁,其中5例小于16岁。因为脊索瘤病程长,大多数病人到本院治疗前已作过多种治疗。 Chordoma is a rare tumor that originates in the residual embryo chordae and grows along the cerebral spinal axis. About 50% of the disease occurred in the sacrococcygeal, 35% occurred in the sphenoid area, 15% occurred in the vertebral body. The general specimen is lobulated cystic mass within the fibrous septum and jelly. Microscopic tumor cells were scattered arrangement, usually irregular and vacuolar, but also showed mucus or amyloidosis. Some cells are poorly differentiated but mostly have no mitoses. Materials and Methods: Anderson Hospital from 1948 to 1976, 19 cases of chordoma admitted, aged 4-80 years, of which 5 were less than 16 years of age. Because of the long course of chordoma, most patients have made many treatments before they come to our hospital for treatment.