目前认为血清胆红素水平是估计原发性胆汁性肝硬化(PBC)预后的一项最敏感指标,但通常在疾病的晚期才会升高。透明质酸盐是一种高分子多糖,主要由间胚叶细胞合成,为肝细胞降解。肝硬化时,病人血清透明质酸盐浓度升高。为探讨血清透明质酸盐对估计 PBC 预后的意义,作者追踪观察66例 PBC 病人。病人和方法 66例中男10、女56例。其中有症状 Serum bilirubin levels are currently considered as one of the most sensitive indicators for estimating the prognosis of primary biliary cirrhosis (PBC), but usually only later in the disease. Hyaluronate is a polymeric polysaccharide that is synthesized mainly by mesodermal cells and degraded by hepatocytes. Liver cirrhosis, the patient’s serum hyaluronate concentration. In order to explore the significance of serum hyaluronate in estimating the prognosis of PBC, the authors followed up 66 patients with PBC. Sixty-six patients were male and 10 were female and 56 were female. There are symptoms