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成人获得性免疫缺陷综合征(AIDS)是以T淋巴细胞缺乏所致的感染为特征的。而小儿AIDS的唯一特征是对与免疫球蛋白(Ig)缺乏有关的感染(即:中耳炎、化脓性肺炎、细菌性败血症等)具有额外的易感性。因为已有报告在复发性化脓性感染病人中,有某种IgG亚型缺乏。所以,对疑似AIDS病的3个婴儿进行了IgG亚型的检测。例1是一个妊娠29周出生的婴儿,在新生儿期曾接受7次输血。9个月时发生复发性中耳炎、鹅口疮、副鼻窦炎和22个月时,发生致死性卡氏肺囊虫肺炎。病例2
Adult acquired immunodeficiency syndrome (AIDS) is characterized by an infection caused by a deficiency of T lymphocytes. The unique feature of pediatric AIDS is the additional susceptibility to infections associated with immunoglobulin (Ig) deficiency (ie, otitis media, suppurative pneumonia, bacterial sepsis, etc.). It has been reported that there is a lack of certain IgG subtype in patients with recurrent purulent infection. Therefore, the detection of IgG subtypes was performed on 3 infants suspected of AIDS. Example 1 was a baby born at 29 weeks of gestation and had 7 transfusions during the neonatal period. Recurrent otitis media, thrush, sinusitis at 9 months and Pneumocystis carinii pneumonia at 22 months. Case 2