因端粒与衰老、肿瘤密切相关,近年来对端粒调节的研究进一步深入。最近发现端粒长度的动态平衡是由端粒、端粒酶、端粒结合蛋白组成的高分子复合体———端粒体调节的。在端粒体中,端粒、端粒酶、端粒结合蛋白相互作用,共同完成对细胞基本生命活动的调节。近年来,分子生物学技术的进展从分子水平上阐明了端粒体各组分间的关系,为端粒长度的调节开辟了新的靶点。 Because telomere is closely related to aging and tumor, the research on telomere regulation has been further studied in recent years. It has recently been found that the dynamic balance of telomere length is regulated by telomeres, telomeres, telomere-binding polymer complexes. In the telomere, telomeres, telomerase, telomere binding protein interactions, together to complete the regulation of the basic life activities of cells. In recent years, advances in molecular biology have elucidated the relationship among various components of telomere at the molecular level, opening up new targets for the regulation of telomere length.