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目的:探讨接受体外受精-胚胎移植(IVF-ET)治疗的男性其发生焦虑、抑郁情绪情况以及治疗结局的影响因素。方法:随机抽取200名接受IVF-ET治疗的男性患者,在治疗周期的第1日完成自行设计的问卷,焦虑自评量表(SAS)、抑郁自评量表(SDS)、Olson-婚姻质量问卷的3个分量表,了解婚姻满意度,夫妻交流,性生活情况。结果:接受IVF-ET男性抑郁发生率达49%,焦虑发生率达27%;焦虑、抑郁得分较高者IVF妊娠失败比例较高(P<0.001);婚姻满意度、夫妻交流、性生活得分值较低的患者IVF妊娠失败比例较高(P<0.001);Logistic回归分析结果显示,人均住房面积、父母对IVF治疗态度、舆论影响、婚姻满意度、抑郁情绪与治疗结局相关。结论:焦虑和抑郁情绪普遍存在于接受IVF-ET治疗的男性患者中,且与妊娠结局有关。因此,不孕生殖中心医务人员对接受IVF-ET治疗的男性在治疗过程中进行心理支持尤为重要。
OBJECTIVE: To investigate the prevalence of anxiety and depression in men undergoing in vitro fertilization-embryo transfer (IVF-ET) and the influencing factors of treatment outcome. METHODS: A total of 200 male patients treated with IVF-ET were randomly selected. A self-designed questionnaire, self-rating anxiety scale (SAS), self-rating depression scale (SDS), Olson-marital quality Questionnaire three subscales to understand marital satisfaction, marital exchange, sexual life. Results: The incidence of depression in IVF-ET male was 49% and the incidence of anxiety was 27%. The higher failure rate of IVF-ET was higher in anxiety and depression patients (P <0.001); marital satisfaction, marital exchange, sexual life IVF rate of pregnancy failure was higher in patients with lower scores (P <0.001). Logistic regression analysis showed that per capita housing area, parental attitude toward IVF, influence of public opinion, marital satisfaction, depression and treatment outcome were correlated. Conclusions Anxiety and depression are common in male patients treated with IVF-ET and are associated with pregnancy outcomes. Therefore, infertility reproductive center medical staff in IVF-ET treatment of men during the psychological support during the treatment is particularly important.