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有关 Tourette 综合征的乙酰胆碱能机理研究一直没有定论。本文报告对6例男性Tourette 综合征患者,采用双盲与安慰剂对照的方法,研究应用毒扁豆碱后所获得的临床改善情况。办法:严格诊断标准且不伴有其他躯体疾病的患者,选择抽动发作频繁及症状持续数小时以上者;对伴有严重的行为
Research on the mechanism of acetylcholine in Tourette’s syndrome has been inconclusive. This article reports on 6 male patients with Tourette’s syndrome, a double-blind and placebo-controlled approach to study the clinical improvement obtained with physostigmine. Approach: strict diagnostic criteria and not associated with other physical diseases in patients with frequent twitch seizures and symptoms persist for more than hours; accompanied by serious behavior