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目的 通过对6 0 Co源事故 3例中重度骨髓型急性放射病 (ARS)患者的剂量估算、临床经过和诊治方法的总结 ,以积累临床资料。方法 依据受照剂量、临床表现、实验室检测结果进行综合分析 ,以明确诊断。治疗上经全环境保护隔离 ,在有指征对症治疗的基础上 ,应用了造血生长因子。结果 3例病人经过 83d住院治疗 ,达到临床治愈。结论 正确的早期分类诊断和初期的积极治疗有利于安全度过极期。女病人如正逢病程极期来月经可给予雄性激素以改变经期 ,可避免大出血。适时足量应用粒 巨噬细胞集落刺激因子 (GM CSF)有助造血功能恢复。
Objective To summarize the dose estimation, clinical experience, and diagnosis and treatment of 3 patients with moderate-severe acute myeloid leukemia (ARS) at 60Co accident in order to accumulate clinical data. Methods According to dose, clinical manifestations, laboratory test results for a comprehensive analysis to confirm the diagnosis. Treatment by the whole environment and isolation, in the indications symptomatic treatment, based on the application of hematopoietic growth factor. Results Three patients were hospitalized after 83 days to reach clinical cure. Conclusion Correct early diagnosis and early diagnosis of positive treatment is conducive to the safety of over-extremes. Female patients such as the very course of the course of menstruation can be given to male hormones to change menstruation, to avoid bleeding. Timely adequate application of granulocyte-macrophage colony-stimulating factor (GM CSF) helps to restore hematopoietic function.