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目的:评价临床药师参与大隐静脉曲张手术围术期预防应用抗菌药物管理的效果。方法:选取2010年6~9月(干预前)、2011年6~9月(干预后)和2014年6~9月(巩固期)出院的大隐静脉单纯剥脱术、大隐静脉高位结扎加剥脱术及大隐静脉高位结扎加静脉内激光治疗的所有病例,针对预防应用抗菌药物的合理性进行评价。结果:临床药师参与管理后,大隐静脉曲张手术围术期预防应用抗菌药物在用药指征、药物品种选择、用法用量、给药途径、溶媒及溶媒量、给药时机、用药疗程、联合用药方面改善明显;抗菌药物使用率、平均住院日、抗菌药物比例、药品比例及输液率均明显降低,并得以巩固。结论:临床药师对大隐静脉曲张手术围术期预防应用抗菌药物的干预,提高了抗菌药物合理使用率,对降低患者费用,规范医院管理有一定意义。
OBJECTIVE: To evaluate the effect of clinical pharmacists in the prevention and treatment of antibiotics administered during perioperative management of saphenous vein varicocele. Methods: From June to September 2010 (before intervention), from June to September 2011 (after intervention) and from June to September 2014 (consolidation period), the saphenous vein was simply exfoliated, the saphenous vein ligation plus Stripping surgery and saphenous vein ligation plus intravenous laser treatment of all cases, the prevention of the rational use of antimicrobial drugs were evaluated. Results: After the clinical pharmacist participated in the management, the application of antimicrobial agents in perioperative prevention and treatment of saphenous varicose vein was indicated in the indications of drug use, drug variety selection, usage dosage, route of administration, amount of vehicle and vehicle, timing of drug delivery, The improvement was obvious. The antibacterial usage rate, the average length of stay, the proportion of antibacterial drugs, the proportion of drugs and the infusion rate were significantly reduced and were consolidated. CONCLUSION: The intervention of clinical pharmacists in the prevention and treatment of saphenous vein varices with perioperative antibacterials improves the rational use of antibacterials, which is of great significance to reducing the cost of patients and standardizing hospital management.