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采用双抗体夹心ＥＬＩＳＡ法对４０例口腔癌患者的血清可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）水平进行测定。结果发现口腔癌患者血清ｓＩＬ－２Ｒ水平显著高于正常对照组（Ｐ＜０．０１），并与临床分期有关；手术后血清ｓＩＬ－２水平较术前明显下降（Ｐ＜０．０１）；４例复发者血清ｓＩＬ－２Ｒ水平又见增高。因此，血清ｓＩＬ－２Ｒ水平的动态观察有助于口腔癌患者预后判断，并可监测复发与转移。
Serum soluble interleukin 2 receptor (sIL-2R) levels were measured in 40 patients with oral cancer using double antibody sandwich ELISA. The level of serum sIL-2R in patients with oral cancer was significantly higher than that in normal controls (P <0.01), and was related to clinical stage. The level of sIL-2 in serum was significantly lower than that before operation (P <0.01). 4 cases of relapse serum sIL-2R level also see increased. Therefore, the dynamic observation of serum sIL-2R level is helpful for the prognosis of oral cancer patients and can monitor the recurrence and metastasis.