Dear Editor,We are reporting you an effective DNA vaccine for FMD virus,and it was prepared using mannosylated chitosan (MC) nanoparticles to form the FMDVpVAC-VP1-OmpA complex particles.These particles were characterized for their physical properties like morphology,size and charge prior evaluating the actual vaccine delivery effect of MC-nanoparticles.The immunological evaluation indicated that the 20 μg Dear Editor, We are reporting DNA vaccine for FMD virus, and it was prepared using mannosylated chitosan (MC) nanoparticles to form the FMDVpVAC-VP1-OmpA complex particles. These particles were characterized for their physical properties like morphology, size and charge prior evaluating the actual vaccine delivery effect of MC-nanoparticles. The immunological evaluation that the 20 μg