复发性阿弗他溃疡(RAU)仍是临床上的一个难题。用药物或不用药物进行预防和治疗,至今成功者极少。在96名成人中进行的6个月的双盲临床研究,对商业上一种有效的抗菌剂漱口液[李司忒抗菌防腐液(LA)]和含水乙醇(hydroalcoholic)漱口液进行了对比,每天漱口2次,以评价易患者RAU的发生率、发病持续时间和严重程度。在统计学上LA漱口液和含水乙醇漱口液使RAU的发生率从基线上明显下降。在溃疡易感者中,使用LA漱口液组,其损害持续时间和疼痛严重 Recurrent aphthous ulcer (RAU) is still a clinical problem. With or without medication for prevention and treatment, few have been successful so far. A six-month double-blind clinical study in 96 adults conducted a commercially effective antibacterial agent mouthwash [LA Legion antimicrobial preservative (LA)] and hydroalcoholic mouthwash In contrast, mouthwash 2 times a day to assess the incidence of RAU susceptible patients, the duration and severity of onset. Statistically LA gargles and aqueous ethanol gargles decreased the incidence of RAU from baseline significantly. In the susceptible to ulcers, the use of LA gargle group, the duration of the injury and severe pain