电磁场(electromagnetic field,EMF)已被证明能影响机体骨代谢,并广泛运用于临床上多种骨骼相关疾病的预防和治疗,包括骨折延迟愈合或不连、新鲜骨折、骨质疏松、先天性假关节等[1-2],但电磁场影响骨形成和骨吸收的潜在机制仍不清楚[3-5]。为明确细胞和分子水平间的相互作用,人 Electromagnetic fields (EMFs) have been shown to affect bone metabolism in the body and are widely used in the prevention and treatment of a variety of bone-related diseases in the clinic, including delayed union or disunion of fractures, fresh fractures, osteoporosis, congenital leave Joints [1-2], but the potential mechanisms by which electromagnetic fields affect bone formation and bone resorption remain unclear [3-5]. To clarify the interaction between cells and molecular levels, humans